Alfentanil – Seek specialist palliative care advice

1mg SC alfentanil = 10mg SC diamorphine = 30mg oral morphine = 15mg SC morphine

Suitable parenteral opioid for use in advanced renal disease under specialist guidance. Alfentanil has a short duration of action which limits its use for breakthrough analgesia.

Note very different dose conversions than Fentanyl (see relative doses of opioids).

Alfentanil and Fentanyl are different drugs.

Alfentanil preparations

Injection (Rapifen®) 500 microgram per ml, 2ml, 10ml ampoules Intensive Care Injection 5mg per ml, 1ml ampoules to be diluted before use.